Detection of human bocavirus in Saudi healthy blood donors
| Autor: | Dalia M. Zytouni, Mohammad E. Mahfouz, Ahmed S. Abdel-Moneim |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male Blood transfusion Sequence analysis medicine.medical_treatment 030106 microbiology Saudi Arabia lcsh:Medicine Blood Donors 030204 cardiovascular system & hematology law.invention 03 medical and health sciences Young Adult 0302 clinical medicine law Human bocavirus Genotype Healthy volunteers medicine Humans lcsh:Science Polymerase chain reaction Whole blood Multidisciplinary biology business.industry lcsh:R Correction Middle Aged biology.organism_classification Healthy Volunteers Healthy individuals Immunology DNA Viral lcsh:Q Female business |
| Zdroj: | PLoS ONE PLoS ONE, Vol 13, Iss 2, p e0193594 (2018) |
| ISSN: | 1932-6203 |
| Popis: | Human bocavirus is associated with respiratory disease worldwide, mainly in children. There are conflicting results, however, regarding the existence of the HBoV in blood donors. Three hundred whole blood samples from non-immunodeficient healthy blood donors were screened for the presence of HBoV by polymerase chain reaction. The HBoV genotype of positive samples was determined using direct gene sequencing. Twenty-one out of the three hundred blood samples were found to be positive for HBoV. Sequence analysis of the positive samples revealed that all the strains were related to the HBoV-1 type with a low rate of variation among the detected sequences. It was concluded that there is a considerable risk of contracting HBoV from a blood transfusion from normal healthy individuals. |
| Databáze: | OpenAIRE |
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