Spatio-temporal expression of a gene encoding a putative RNA-binding protein during the early larval development of the mollusc Patella vulgata
| Autor: | André E. van Loon, Esther de Boer, Anke H.E.M. Klerkx |
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| Rok vydání: | 2001 |
| Předmět: |
Embryo
Nonmammalian Sequence analysis Molecular Sequence Data RNA-binding protein Genetics Animals Humans Amino Acid Sequence RNA Messenger Cloning Molecular Monensin Gene In Situ Hybridization Larva Sequence Homology Amino Acid biology Gene Expression Regulation Developmental RNA-Binding Proteins Cell Differentiation biology.organism_classification Molecular biology KH domain Mollusca Trochophore Patella vulgata Developmental biology Developmental Biology |
| Zdroj: | Development Genes and Evolution. 211:423-427 |
| ISSN: | 1432-041X 0949-944X |
| DOI: | 10.1007/s004270100170 |
| Popis: | In the mollusc Patella vulgata a cDNA clone named Esther 32 (E32) was found to be expressed in a specific spatio-temporal pattern. DNA sequence analysis showed that E32 represents a putative RNA-binding protein containing a KH domain. In early trochophore larvae, expression of E32 was found in all cells except the already differentiated trochoblasts and the apical tuft cells. Later on in development, expression was also abolished in the presumptive shell gland and restricted to specific areas, among which were the head and foot anlage. This suggests that E32 is involved in maintaining cells in an undifferentiated state via a post-transcriptional mechanism. |
| Databáze: | OpenAIRE |
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