Anxiolytic activity of diterpene alkaloid songorine

Autor:	S. G. Aksinenko, O. G. Afanas’eva, Elvira E. Shults, T. N. Povet’eva, Yu. V. Nesterova, T. G. Kharina, A. V. Krapivin, G. N. Ziuz’kov, N. I. Suslov
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Male Sedative effect medicine.drug_class Anxiolytic General Biochemistry Genetics and Molecular Biology Conflict Psychological Benzodiazepines Mice chemistry.chemical_compound Alkaloids Vogel Conflict Test medicine Animals анксиолитическая активность Aconitum Behavior Animal Dose-Response Relationship Drug biology Traditional medicine Alkaloid Phenazepam General Medicine biology.organism_classification Anti-Anxiety Agents chemistry Conflict (Psychology) Mice Inbred CBA дитерпреновые алкалоиды Diterpenes Diterpene Stress Psychological medicine.drug
Zdroj:	Bulletin of experimental biology and medicine. 2015. Vol. 159, № 5. P. 620-622
Popis:	Antianxiety action of diterpene alkaloid songorine was studied using Vogel conflict test. Songorine in a dose of 0.25 mg/kg demonstrated high anxiolytic activity comparable to that of phenazepam and produced no sedative effect.
Databáze:	OpenAIRE
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