Two 14q+ chromosomes in malignant lymphoma: Crucial cytogenetic changes on 14q
| Autor: | Mitsuaki A. Yoshida, Avery A. Sandberg, Kazuma Ohyashiki, Tin Han, Junko H. Ohyashiki, Frederick Koch |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty White male Chromosomal translocation Biology Translocation Genetic Malignant lymphoma Genetics medicine Humans skin and connective tissue diseases Molecular Biology Lymph node Lymphoma Non-Hodgkin Poorly differentiated Cytogenetics Chromosome Mapping Chromosome Gene rearrangement Molecular biology Chromosome Banding medicine.anatomical_structure Karyotyping Cancer research sense organs Chromosomes Human 13-15 |
| Zdroj: | Cancer Genetics and Cytogenetics. 17:325-331 |
| ISSN: | 0165-4608 |
| DOI: | 10.1016/0165-4608(85)90116-5 |
| Popis: | We encountered a 36-year-old white male patient with poorly differentiated lymphocytic lymphoma, whose lymph node cells showed a clonal cytogenetic change involving chromosome #14, i.e., 47,XY, + 2,der(14),t(14;14)(14pter----14q32;14q24----14q32++ +). In addition to this change, cells with a translocation between chromosomes #2 and another #14 [t(2;14)(q21;q24)], as well as a missing chromosome #8 were found. We have reviewed the literature dealing with two or more changes affecting chromosome #14 and discussed the importance of the cytogenetic change at band 14q32 in malignant lymphoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|