Quantitative profiling of comprehensive composition in compound herbal injections: An NMR approach applied on Shenmai injection

Autor:	Wenzhu Li, Fang Zhao, Xinyuan Xie, Jiayu Yang, Jianyang Pan, Haibin Qu
Rok vydání:	2022
Předmět:	Magnetic Resonance Spectroscopy Plants Medicinal Ginsenosides Polysorbates Reproducibility of Results Plant Science General Medicine Biochemistry Analytical Chemistry Drug Combinations Complementary and alternative medicine Drug Discovery Molecular Medicine Protons Drugs Chinese Herbal Food Science
Zdroj:	Phytochemical Analysis. 33:1045-1057
ISSN:	1099-1565 0958-0344
Popis:	Compound herbal injections (CHIs) can be regarded as a significant innovation in the modernisation of herbal medicine. Therefore, improving the quality control level of CHIs has always been an active research topic in traditional herbal medicine.In this study, Shenmai injection was used as a representative sample for investigating the ability of proton nuclear magnetic resonance (A quantitativeIt was found that the combined measurement uncertainty of each component is less than 1.61%, which demonstrates the reliability of the method. Furthermore, the components determined by this method account for up to 92.64% of the total solids, which is an unprecedented success in the analysis of Shenmai injection. In the end, the method was applied to the quality comparison of Shenmai injection from six manufacturers. The results showed that the differences among the samples from the six manufacturers were reflected in multiple types of components.This study fully demonstrates the superiority of the quantitative
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ca4a4c4446fa9f6cfa7f6885c351bf https://doi.org/10.1002/pca.3158 Zobrazit plný text záznamu Plný text