The effect of cadmium exposition on the structure and mechanical properties of rat incisors
Autor: | Krystian J. Cieślak, Jose Luis Valverde Piedra, Adam Prószyński, Siemowit Muszyński, Ewa Tomaszewska, Daniel Kamiński, Michał Świetlicki, Dariusz Wiącek, Izabela Świetlicka, Sylwia Szymańczyk |
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Rok vydání: | 2019 |
Předmět: |
Male
inorganic chemicals Science CADMIUM TOXICITY chemistry.chemical_element Microscopy Atomic Force 03 medical and health sciences 0302 clinical medicine Animal science X-Ray Diffraction stomatognathic system Hardness Animals Rats Wistar Dental Enamel 030304 developmental biology Minerals 0303 health sciences Cadmium Multidisciplinary Enamel paint Chemistry 030206 dentistry Biomechanical Phenomena Rats Incisor stomatognathic diseases Durapatite visual_art Microscopy Electron Scanning visual_art.visual_art_medium Medicine Female Crystallization |
Zdroj: | PLoS ONE, Vol 14, Iss 4, p e0215370 (2019) |
ISSN: | 1932-6203 |
Popis: | Alterations in the structure and mechanical properties of teeth in adult Wistar rats exposed to cadmium were investigated. Analyses were conducted on two sets of incisors from female and male specimens, that were intoxicated with cadmium (n = 12) or belonged to the control (n = 12). The cadmium group was administered with CdCl2 dissolved in drinking water with a dose of 4mg/kgbw for 10 weeks. The oral intake of cadmium by adult rats led to the range of structural changes in enamel morphology and its mechanical features. A significant increase of cadmium levels in the teeth in comparison to the control, a slight shift in the colour and reduction of pigmented enamel length, higher surface irregularity, a decrease of hydroxyapatite crystals size in the c-axis and simultaneous increase in pigmented enamel hardness were observed. The extent of these changes was sex-dependent and was more pronounced in males. |
Databáze: | OpenAIRE |
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