Prognostic significance of oestrogen uptake by human breast-cancer tissue
| Autor: | V.H.T. James, R.A. Sellwood, W.T. Irvine, Frances James, C.W. Jamieson, A. E. Carter, M. Hulbert, Hannelore Braunsberg |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Diethylstilbestrol Physiology Breast Neoplasms Tritium Breast cancer In vivo Internal medicine medicine Endocrine system Humans Breast Neoplasm Metastasis Mastectomy Aged Hypophysectomy Estradiol business.industry Ovary Cancer Adrenalectomy Estrogens General Medicine Middle Aged medicine.disease Prognosis Clinical research Endocrinology Androgen Therapy Neoplasm Regression Spontaneous Female business Hormone medicine.drug |
| Zdroj: | Lancet (London, England). 1(7796) |
| ISSN: | 0140-6736 |
| Popis: | The uptake of radio-labelled œstradiol by human breast-tumour tissue in vivo has been studied in relation to the response of the patient to endocrine therapy. Patients with a low uptake of œstradiol tended not to respond favourably to endocrine ablation or to androgen therapy. The converse was not true; high œstradiol uptake was found in several patients who did not respond to treatment. |
| Databáze: | OpenAIRE |
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