Ubiquitous atherosclerosis in coronary arteries without angiographically significant stenosis
| Autor: | Tatsuhiko Asano, Hideki Kitahara, Naoki Ishio, Kenichi Fukushima, Yoshio Kobayashi, Yo Iwata, Issei Komuro, Takashi Nakayama, Nakabumi Kuroda |
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| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Lumen (anatomy) Coronary Artery Disease Coronary Angiography Severity of Illness Index Coronary artery disease Predictive Value of Tests Internal medicine Intravascular ultrasound medicine Humans Ultrasonography Interventional Aged medicine.diagnostic_test business.industry Coronary Stenosis Middle Aged Vascular surgery medicine.disease Cardiac surgery Coronary arteries Stenosis medicine.anatomical_structure Angiography Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Heart and Vessels. 25:35-40 |
| ISSN: | 1615-2573 0910-8327 |
| Popis: | Previous intravascular ultrasound (IVUS) studies have shown coronary artery atherosclerosis even in angiographically normal reference segment. However, IVUS has not been performed in all of the three major coronary arteries. A total of 50 patients with single-vessel disease underwent IVUS evaluation in the proximal two-thirds of the three major coronary arteries. Lumen and external elastic membrane cross-sectional areas were measured at 1-mm intervals. To compensate the difference in pullback length among coronary arteries, normalized total plaque and media volume (TPV) was calculated as TPV/number of slices in pullback x median number of slices in study population. Percent plaque and media volume (PPV) was calculated as TPV/Sigma external elastic membrane cross-sectional area x 100. A cross section was defined as atherosclerotic if maximum intimal thickness exceeded 0.5 mm at any point in the vessel circumference. There was no significant difference in normalized TPV, PPV, and the incidence of abnormal intimal thickness between coronary arteries with and without significant stenosis. Frequency distribution of plaque burden was similar. Atherosclerosis is ubiquitous even in coronary arteries without angiographically significant stenosis. The extent of atherosclerosis is similar between coronary arteries with and without significant stenosis. |
| Databáze: | OpenAIRE |
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