Children with vaccination granulomas and aluminum contact allergy: Evaluation of predispositions, avoidance behavior, and quality of life
| Autor: | Stine Skovbo Hoffmann, Jeanne D. Johansen, Kirsten Hansen, Jesper Elberling, Jacob P. Thyssen |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Quality of life Risk Factors Surveys and Questionnaires Avoidance Learning Humans Immunology and Allergy Medicine 030212 general & internal medicine Child Allergic contact dermatitis Reference group Vaccines Granuloma business.industry Pruritus Vaccination Infant medicine.disease Immunization Child Preschool Dermatitis Allergic Contact Cohort Quality of Life Itching Female medicine.symptom business Sunscreening Agents Aluminum |
| Zdroj: | Contact Dermatitis. 83:99-107 |
| ISSN: | 1600-0536 0105-1873 |
| Popis: | BACKGROUND Aluminum contact allergy is mostly seen in children with vaccination granulomas, following immunization with aluminum-adsorbed childhood vaccines. OBJECTIVES To characterize a cohort of children with vaccination granulomas and aluminum allergy concerning early life conditions, exacerbating factors, avoidance behavior, treatments, and potential impact on quality of life. METHODS A questionnaire study was conducted among 177 children aged 0 to 15 years with vaccination granulomas and aluminum allergy, and a reference group of 61 children aged 3 to 14 years with various types of dermatitis undergoing patch testing. RESULTS All children in the granuloma group were reportedly affected by itch. Infection exacerbated the itch in 59%. Other worsening factors were eating tin-foiled/canned food (31%) and use of aluminum-containing sunscreen (46%). Many parents took precautions to avoid aluminum exposure. Children with granulomas were more likely to be nonadherent to the National Vaccination Program than the reference group (27% vs 2%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|