Latex hypersensitivity in Department of Veterans Affairs health care workers: glove use, symptoms, and sensitization

Autor: Diane Foster, Frances M. Murphy, Robert K. Bush, Karen Kestenberg, David N. Weissman, Jordan N. Fink, Kevin J. Kelly, Kathleen Colella, C.Raymond Zeiss, Michael J. Hodgson, Viswanath P. Kurup, Asriani Chiu, Ahmed Gomaa, Sang Dejativongse
Rok vydání: 2003
Předmět:
Hypersensitivity
Immediate

Male
Allergy
Time Factors
Latex Hypersensitivity
Statistics as Topic
medicine.disease_cause
Atopy
Allergen
Surveys and Questionnaires
Prevalence
Immunology and Allergy
Medicine
Sensitization
education.field_of_study
Middle Aged
Occupational Diseases
United States Department of Veterans Affairs
Treatment Outcome
medicine.anatomical_structure
Dermatitis
Allergic Contact

Female
National Institute for Occupational Safety and Health
U.S

Adult
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Health Personnel
Immunology
Population
Sensitivity and Specificity
Occupational medicine
Predictive Value of Tests
Occupational Exposure
Humans
False Positive Reactions
education
Veterans Affairs
Aged
business.industry
technology
industry
and agriculture

Immunoglobulin E
equipment and supplies
medicine.disease
Dermatology
United States
body regions
Immunization
Centers for Disease Control and Prevention
U.S

Gloves
Protective

business
Biomarkers
Zdroj: Annals of Allergy, Asthma & Immunology. 91:539-545
ISSN: 1081-1206
Popis: Background This report of the prevalence of latex glove allergy in 3 Department of Veterans Affairs (VA) medical centers was a collaboration of the VA, the Centers for Disease Control and Prevention, and the National Institute for Occupational Safety and Health. Objectives To enroll and evaluate personnel from across the entire hospital workforce for latex hypersensitivity and to determine the type and extent of latex glove use. Methods A questionnaire was administered that covered demographics, job category, latex glove use, and current latex glove allergic symptoms. Skin testing to aeroallergens was performed to evaluate the presence of atopy. Blood was drawn for analyses of serum antilatex IgE antibody by CAP assay. Results Of 1,959 subjects, 158 (8.1%) had latex glove-allergic symptoms, a positive latex CAP assay result, or both. In 1,003 subjects who reported latex glove use, 915 (91.4%) used nonpowdered gloves. A total of 133 subjects reported latex glove allergic symptoms, and 36 subjects had positive CAP assay results. Latex sensitization was correlated with atopy, race, and latex glove exposure. Latex symptoms were correlated with atopy, a positive CAP assay result, and latex glove exposure. Of the 133 subjects with latex glove allergic symptoms, only 11 had positive CAP assay results, giving a prevalence of confirmed latex glove allergy of 0.6%. Conclusions Symptoms attributed to latex gloves and/or latex sensitization occurred in 8.1% of the employee population, with exposure, race, and atopy being the major risk factors. Few symptomatic individuals were sensitized to latex (0.6%). This low rate of confirmed latex glove allergy may have been related to nonpowdered glove use.
Databáze: OpenAIRE