Total Thyroidectomy is Associated with Increased Prevalence of Permanent Hypoparathyroidism
| Autor: | Marcin Barczyński, Aneta Pragacz, Wiesław Grzesiuk, Ireneusz Nawrot, Krzysztof Pragacz |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Hypoparathyroidism medicine.medical_treatment Young Adult Postoperative Complications Clinical Research Prevalence medicine Humans Endocrine system Aged Demography Aged 80 and over Hypocalcemia business.industry Incidence Incidence (epidemiology) Thyroid Thyroidectomy General Medicine Middle Aged medicine.disease Thyroid disorder Surgery Logistic Models medicine.anatomical_structure Multivariate Analysis Cohort Female Complication business |
| Zdroj: | ResearcherID Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| Popis: | BACKGROUND Thyroid disorders are very common in adults. Despite advances in conservative management, surgery remains a treatment modality of choice in many cases. The mortality and morbidity of thyroidectomy are low, but long-term postoperative hypoparathyroidism (HPT) remains a prominent complication of the procedure. The aim of this study was to assess the incidence of permanent HPT and identify the risk factors for this complication in a cohort of post-thyroidectomy patients followed at a District Endocrine Clinic. MATERIAL AND METHODS This was a retrospective analysis of 401 patients followed up at a Regional/District Endocrine Clinic, who had undergone thyroid surgery in the years 1993-2011. The percentage of patients with permanent (>12 months) HPT was the primary endpoint of the study. The statistically analyzed data of patients with permanent HPT versus the remaining patients free from postoperative complications included their demographic data, indications for surgical treatment of their thyroid disorder, and extent of the thyroid resection. The risk factors for postoperative hypoparathyroidism were assessed using logistic regression analysis. RESULTS Permanent HPT following surgery on the thyroid gland occurred in 8.5% of the patients. It was more frequent following total thyroidectomy (20.2%) than near-total thyroidectomy (6.7%) or subtotal thyroidectomy (4.2%); p |
| Databáze: | OpenAIRE |
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