Síndrome neuroléptico maligno y poliserositis en paciente usuaria de clozapina: una asociación infrecuente

Autor: Gonzalo Eymin L, Gabriel Rada G, Max Andresen H, Jaime Godoy F
Rok vydání: 2005
Předmět:
Zdroj: Revista médica de Chile v.133 n.10 2005
SciELO Chile
CONICYT Chile
instacron:CONICYT
ISSN: 0034-9887
DOI: 10.4067/s0034-98872005001000012
Popis: Malignant neuroleptic syndrome is a complication of antipsychotic medication use. Clozapine use is also associated with polyserositis and eosinophilia. We report a 17 years old female treated with clozapine, valproic acid, lithium carbonate and lorazepam that consulted in the emergency room for confusion, lethargy, catatonia, rigidity, myalgya and fever. Complete blood count showed eosinophilia. An abdominal CAT scan showed ascites and pleural effusion. Clozapine was discontinued and bromocriptine was started. One week after admission, the patient remained febrile and liver enzymes were elevated. Valproic acid was discontinued. Inflammatory parameters stated to subside and the patient was discharged afebrile days after admission (Rev Méd Chile 2005; 133: 1225-8)
Databáze: OpenAIRE