Viral Infection in Renal Transplant Recipients
| Autor: | Jovana Cukuranovic, Sladjana Ugrenović, Vladisav Stefanovic, Milan Visnjic, Ivan Jovanović |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Opportunistic infection
viruses Congenital cytomegalovirus infection lcsh:Medicine Review Article Opportunistic Infections Biology Kidney lcsh:Technology Viral infection General Biochemistry Genetics and Molecular Biology Virus Immune system medicine Humans lcsh:Science Kidney transplantation General Environmental Science lcsh:T lcsh:R General Medicine medicine.disease Kidney Transplantation Virology Transplantation Virus Diseases Renal transplant Immunology lcsh:Q |
| Zdroj: | The Scientific World Journal The Scientific World Journal, Vol 2012 (2012) |
| ISSN: | 1537-744X |
| DOI: | 10.1100/2012/820621 |
| Popis: | Viruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility. Although cytomegalovirus is the most common opportunistic pathogen seen in transplant recipients, numerous other viruses have also affected outcomes. In some cases, preventive measures such as pretransplant screening, prophylactic antiviral therapy, or posttransplant viral monitoring may limit the impact of these infections. Recent advances in laboratory monitoring and antiviral therapy have improved outcomes. Studies of viral latency, reactivation, and the cellular effects of viral infection will provide clues for future strategies in prevention and treatment of viral infections. This paper will summarize the major viral infections seen following transplant and discuss strategies for prevention and management of these potential pathogens. |
| Databáze: | OpenAIRE |
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