4-Hydroxybutyrate Promotes Endogenous Antimicrobial Peptide Expression in Macrophages

Autor:	Derek S. Wang, Denver M. Faulk, Brian M. Sicari, Ross M Giglio, Stephen F. Badylak, Jonas Eriksson, George S. Hussey, Catalina Pineda Molina, Riddhi M Gandhi, Michael A Shulock, Laura L Cárdenas Bonilla, Ricardo Londono, Neill J. Turner
Rok vydání:	2019
Předmět:	Cell type beta-Defensins 0206 medical engineering Antimicrobial peptides Biomedical Engineering Hydroxybutyrates Bone Marrow Cells Bioengineering Endogeny 02 engineering and technology Biochemistry Rats Sprague-Dawley Biomaterials Mice 03 medical and health sciences chemistry.chemical_compound Cathelicidins Animals 030304 developmental biology 0303 health sciences Innate immune system Effector Macrophages Sodium butyrate Antimicrobial 2-Hydroxybutyrate 020601 biomedical engineering Rats chemistry Antimicrobial Cationic Peptides
Zdroj:	Tissue Engineering Part A. 25:693-706
ISSN:	1937-335X 1937-3341
DOI:	10.1089/ten.tea.2018.0377
Popis:	Naturally occurring antimicrobial peptides (AMPs) are effector molecules secreted by several cell types but especially by cells of the innate immune system such as macrophages. AMPs largely avoid r...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7875a28094d5e75e4b2e74373f2f8c9 https://doi.org/10.1089/ten.tea.2018.0377 Zobrazit plný text záznamu