Novelty Detection in the Human Auditory Brainstem
| Autor: | Lavinia Slabu, Sabine Grimm, Carles Escera |
|---|---|
| Přispěvatelé: | Institute for Brain, Cognition, and Behavior (IR3C), and Cognitive Neuroscience Research Group, Department of Psychiatry and Clinical Psychobiology, University of Barcelona, 08035 Barcelona, Catalonia-Spain |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Thalamus Mismatch negativity Deviance (statistics) Audiology Auditory cortex 050105 experimental psychology Midbrain Young Adult 03 medical and health sciences 0302 clinical medicine Evoked Potentials Auditory Brain Stem Reaction Time medicine Humans Speech 0501 psychology and cognitive sciences General Neuroscience [SCCO.NEUR]Cognitive science/Neuroscience 05 social sciences medicine.anatomical_structure Acoustic Stimulation Scalp [SCCO.PSYC]Cognitive science/Psychology Auditory Perception Female Brainstem Syllable Brief Communications Psychology 030217 neurology & neurosurgery Brain Stem |
| Zdroj: | Journal of Neuroscience Journal of Neuroscience, Society for Neuroscience, 2012, 32 (4), pp.1447-1452. ⟨10.1523/JNEUROSCI.2557-11.2012⟩ |
| ISSN: | 0270-6474 1529-2401 |
| DOI: | 10.1523/JNEUROSCI.2557-11.2012⟩ |
| Popis: | Auditory deviance detection has been associated with a human auditory-evoked potential (AEP), the mismatch negativity, generated in the auditory cortex 100–200 ms from sound change onset. Yet, single-unit recordings in animals suggest much earlier (∼20–40 ms), and anatomically lower (i.e., thalamus and midbrain) deviance detection. In humans, recordings of the scalp middle-latency AEPs have confirmed early (∼30–40 ms) deviance detection. However, involvement of the human auditory brainstem in deviance detection has not yet been demonstrated. Here we recorded the auditory brainstem frequency-following response (FFR) to consonant-vowel stimuli (/ba/, /wa/) in young adults, with stimuli arranged in oddball and reversed oddball blocks (deviant probability,p= 0.2), allowing for the comparison of FFRs to the same physical stimuli presented in different contextual roles. Whereas no effect was observed for the /wa/ syllable, we found for the /ba/ syllable a reduction in the brainstem FFR to deviant stimuli compared with standard ones and to similar stimuli arranged in a control block, with five equiprobable, rarely occurring sounds. These findings demonstrate that the human auditory brainstem is able to encode regularities in the recent auditory past to detect novel events, and confirm the multiple anatomical and temporal scales of human deviance detection. |
| Databáze: | OpenAIRE |
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