Sensation of Cold during the Ice Water Test Corresponds to the Perception of Pain during Botulinum Toxin Bladder Wall Injections
Autor: | Regula Doggweiler, André Reitz, Stephan Buse, Tanja Hüsch, Axel Haferkamp |
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Rok vydání: | 2017 |
Předmět: |
Adult
Male Pain Threshold Botulinum Toxins Urology Urinary Bladder 030232 urology & nephrology Acetylcholine Release Inhibitors 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Sensation Medicine Pain perception Humans In patient Thermosensing Neurons Afferent Aged Pain Measurement Urinary bladder business.industry Urinary Bladder Overactive Ice Water Diagnostic Techniques Urological Pain Perception Pain scale Middle Aged medicine.disease Botulinum toxin Ice water medicine.anatomical_structure Administration Intravesical Overactive bladder Anesthesia Female business 030217 neurology & neurosurgery medicine.drug |
Zdroj: | Urologia internationalis. 100(2) |
ISSN: | 1423-0399 |
Popis: | Aims: To investigate the association of bladder cold sensation (BCS) during the ice water test (IWT) and pain perception when botulinum toxin injections (BTI) are administered into the bladder wall. Material and Methods: In 86 patients with idiopathic overactive bladder, the BCS during the IWT was investigated. Patients were divided into 2 groups: with and without BCS. During subsequent administration of BTI, the number of perceived and painful injections as well as the pain levels on a 0-100 pain scale were compared in both groups using Student t test. Results: Thirty-five patients reported a BCS, while 51 did not. After 10 BTI, the mean number of perceived injections was 7.9 in patients with and 2.4 in patients without BCS (p < 0.0001). The mean number of painful injections was 5.4 in patients with BCS and 4.3 in patients without (p < 0.001). Mean levels on a 0-100 pain scale were 33.7 in patients with and 17.8 in patients without cold sensation (p < 0.0001). Conclusion: The association of BCS during the IWT and pain to during BTI may implicate that the perceptions of cold and pain in the urinary bladder may use similar receptors and neuronal pathways. |
Databáze: | OpenAIRE |
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