Cutaneous angioma in Crow-Fukase syndrome: the nature of globules within the endothelial cells
| Autor: | Takashi Anzai, Syozo Sato, Yoko Hayashi, Kumiko Jitsukawa |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Skin Neoplasms Crow-Fukase Syndrome Dermatology Immunoglobulin light chain Endocrine System Diseases Skin Diseases law.invention Angioma law medicine Humans Endothelium Silver particles chemistry.chemical_classification Peripheral Nervous System Diseases General Medicine Syndrome medicine.disease Staining chemistry Immunohistochemistry Female Electron microscope Glycoprotein Hemangioma |
| Zdroj: | The Journal of dermatology. 15(6) |
| ISSN: | 0385-2407 |
| Popis: | To clarify the nature of the intracytoplasmic globules seen in the endothelial cells of the cutaneous angiomas of the Crow-Fukase syndrome, we performed light and electron microscopic as well as immunohistochemical studies. The proliferating plump endothelial cells of the angioma located in the mid-dermal portion contained numerous globules. IgG, A, M, and kappa and lambda light chain globulins were present in the endothelial cells containing these globules. Electron microscopy revealed osmiophilic fine fibrillar structures and amorphous substance in the globules. Thiery staining for detection of vicinal-glycol radicals of carbohydrate demonstrated the deposition of fine silver particles as a reaction product. We consider that the intracytoplasmic globules are phagolysosomes containing glycoprotein. |
| Databáze: | OpenAIRE |
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