Interaction of high-molecular-weight adiponectin concentration in blood serum with the risk of metabolic syndrome in women
| Autor: | T. L. Karonova, O. A. Berkovich, D. L. Brovin, O D Belyaeva, N. A. Korelskaya |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Medicine (General) genetic structures adiponectin business.industry medicine.disease metabolic syndrome abdominal obesity Endocrinology Blood serum high molecular weight adiponectin R5-920 High molecular weight adiponectin Internal medicine Medicine Metabolic syndrome business |
| Zdroj: | Učenye Zapiski Sankt-Peterburgskogo Gosudarstvennogo Medicinskogo Universiteta im. Akad. I.P. Pavlova, Vol 28, Iss 1, Pp 32-39 (2021) |
| ISSN: | 1607-4181 |
| Popis: | Introduction. The development of metabolic syndrome (MS) in patients with abdominal obesity (AO) may be associated with a low level of the adiponectin (AN) - protective adipocytokine. AN circulates in the blood in various molecular forms.The high molecular weight AN is assumed to have greater metabolic activity. It is currently not clear what level of high molecular weight adiponectin (HMWA) in women with AO is associated with MS and its components.The objective was to study the role of high molecular weight adiponectin in the development of metabolic syndrome in women with abdominal obesity.Methods and materials. 302 women with AO and 161 women without AO were examined. MS was diagnosed in 62.3 % of patients.Results. The concentration of total adiponectin (TAN) and HMAN in the blood serum in women with MS was lower than in patients without MS (pConclusions. It was found that women with AO and HMAN concentration of less than 1.96 μg/ml in the blood had an increased risk of metabolic syndrome. |
| Databáze: | OpenAIRE |
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