13C-urea breath test results in pigs challenged withHelicobacter pylorior other urease producing bacteria
| Autor: | Lars Engstrand, Helena Berglund, Piotr Tracz, Wolfgang Kraaz, Sven Gustafsson, Helena Enroth, Mats Bergström |
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| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Helicobacter pylori infection Urease Swine Immunology Microbiology Gastroenterology Helicobacter Infections 13C urea breath test Internal medicine Flora (microbiology) medicine Animals Urea Immunology and Allergy Breath test Carbon Isotopes Helicobacter pylori biology medicine.diagnostic_test Pig model General Medicine biology.organism_classification Infectious Diseases biology.protein Female Bacteria |
| Zdroj: | FEMS Immunology & Medical Microbiology. 23:253-257 |
| ISSN: | 1574-695X 0928-8244 |
| DOI: | 10.1111/j.1574-695x.1999.tb01246.x |
| Popis: | The gastric bacterial flora and its influence on the 13C-urea breath test (UBT) for detection of Helicobacter pylori infection was studied in a pig model. Seven SPF minipigs were used. H. pylori or a mix of other urease positive bacteria were administered orally. UBT, serum and biopsies for histology and culture were collected. Our results show that UBT is not specific for H. pylori in pigs as the gastric bacterial flora is responsible for the high UBT values observed. Furthermore, the Ellegaard Göttingen SPF minipigs are not useful in an animal model for H. pylori studies. |
| Databáze: | OpenAIRE |
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