Utilization of voriconazole drug monitoring in the treatment of cutaneous Scedosporium apiospermum infection
| Autor: | Harry Dao, Vagish Hemmige, McKenna Boyd, Jerry D. Estep, Yve Huttenbach |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Drug medicine.medical_specialty Right shin media_common.quotation_subject medicine.medical_treatment 030106 microbiology Microbiology 03 medical and health sciences 0302 clinical medicine medicine 030212 general & internal medicine Dosing lcsh:QH301-705.5 media_common Voriconazole Heart transplantation lcsh:R5-920 medicine.diagnostic_test business.industry Scedosporium apiospermum Dermatology Infectious Diseases lcsh:Biology (General) Nodular lesions Therapeutic drug monitoring business lcsh:Medicine (General) medicine.drug |
| Zdroj: | Medical Mycology Case Reports, Vol 22, Iss, Pp 52-54 (2018) |
| ISSN: | 2211-7539 |
| Popis: | We report the use of voriconazole troughs to achieve appropriate therapeutic levels in treatment of a cutaneous Scedosporium apiospermum infection. Following heart transplantation, a 63-year-old immunocompromised patient presented with post-traumatic nodular lesions on his right shin. Pathology showed fungal yeasts with culture revealing Scedosporium apiospermum. According to therapeutic drug monitoring, initial voriconazole treatment was subtherapeutic requiring increased dosing until appropriate therapeutic trough levels were attained, and resolution of the fungal infection was achieved. Keywords: Cutaneous Scedosporium apiospermum, Voriconazole, Trough, Transplant, Immunocompromised |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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