Contemporary management of the neck in nasopharyngeal carcinoma
| Autor: | Andrés Coca-Pelaz, Avraham Eisbruch, Remco de Bree, Sandra Nuyts, Ricard Simo, Juan P. Rodrigo, Wai Tong Ng, Primož Strojan, K. Thomas Robbins, Raymond K. Y. Tsang, Jonathan J. Beitler, Antti Mäkitie, Robert P. Takes, Anne W.M. Lee, Carl E. Silver, William M. Mendenhall, Alfio Ferlito, Orlando Guntinas-Lichius, Robert Smee, Alessandra Rinaldo |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Standard of care Nodal irradiation medicine.medical_treatment Normal tissue 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Humans Neoplasm Staging Nasopharyngeal Carcinoma business.industry Nodal metastasis Carcinoma Treatment options Nasopharyngeal Neoplasms medicine.disease 3. Good health Radiation therapy Otorhinolaryngology Nasopharyngeal carcinoma 030220 oncology & carcinogenesis Lymphatic Metastasis Radiology NODAL business Neck Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
| Zdroj: | Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 43, 1949-1963 Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 43, 6, pp. 1949-1963 |
| ISSN: | 1043-3074 |
| Popis: | Item does not contain fulltext Up to 85% of the patients with nasopharyngeal carcinoma present with regional nodal metastasis. Although excellent nodal control is achieved with radiotherapy, a thorough understanding of the current TNM staging criteria and pattern of nodal spread is essential to optimize target delineation and minimize unnecessary irradiation to adjacent normal tissue. Selective nodal irradiation with sparing of the lower neck and submandibular region according to individual nodal risk is now emerging as the preferred treatment option. There has also been continual refinement in staging classification by incorporating relevant adverse nodal features. As for the uncommon occurrence of recurrent nodal metastasis after radiotherapy, surgery remains the standard of care. |
| Databáze: | OpenAIRE |
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