Herpes Virus Type 2 Infection and Genital Symptoms in Primary Care Patients

Autor: Douglas T. Fleming, Dominick Esposito, Stephanie Chin, Peter A. Leone, Cathy K. Heitman, Kenneth H. Fife, Scott E. Justus
Rok vydání: 2006
Předmět:
Zdroj: Sexually Transmitted Diseases. 33:416-421
ISSN: 0148-5717
Popis: Objective We aimed to identify whether genital symptoms were associated with unrecognized herpes simplex virus type 2 (HSV-2) infection in a primary care population. Study design Five thousand four hundred fifty-two individuals aged 18 to 59 seeking general care at 36 suburban medical offices in 6 U.S. cities were tested for HSV-2 antibody and asked about 10 types of genital symptoms. In patients with no known history of genital herpes, we assessed whether HSV-2 infection was independently associated with symptoms. Results HSV-2 infection was associated with increases in reports of "sores, blisters, ulcers, crusts, or small cuts/slits" in men [adjusted odds ratio (OR), 1.79; 95% CI, 1.24-2.58] and with increases in reports of "redness, irritation, or a rash" among women (adjusted OR, 1.50; 95% CI, 1.06-2.11). HSV-2 was not significantly associated with other types of genital symptoms. Conclusions Primary-care physicians should consider unrecognized HSV-2 infection as a potential cause of some common genital symptoms.
Databáze: OpenAIRE