Can early MRI distinguish between Kingella kingae and Gram-positive cocci in osteoarticular infections in young children?

Autor: David Laurent Tchernin, Dimitri Ceroni, Laura Merlini, Sylviane Hanquinet, Aikaterini Kanavaki
Jazyk: angličtina
Rok vydání: 2012
Předmět:
musculoskeletal diseases
Male
Neisseriaceae Infections/microbiology/pathology
medicine.medical_specialty
Pathology
Osteitis/microbiology/pathology
Neisseriaceae Infections
Arthritis
Kingella kingae
ddc:616.0757
Sensitivity and Specificity
Diagnosis
Differential
Gram-Positive Cocci/isolation & purification
Kingella kingae/isolation & purification
medicine
Humans
Radiology
Nuclear Medicine and imaging
Gram-Positive Cocci
Gram-Positive Bacterial Infections
Osteitis
Neuroradiology
Arthritis
Infectious
ddc:618
biology
business.industry
Cartilage
Soft tissue
Infant
Reproducibility of Results
Joint effusion
biology.organism_classification
medicine.disease
Surgery
medicine.anatomical_structure
Early Diagnosis
Epiphysis
Gram-Positive Bacterial Infections/microbiology/pathology
Child
Preschool
Pediatrics
Perinatology and Child Health
Arthritis
Infectious/microbiology/pathology
Female
medicine.symptom
business
Zdroj: Pediatric Radiology, Vol. 42, No 1 (2012) pp. 57-62
ISSN: 0301-0449
Popis: Background: K. kingae is a common causative organism in acute osteoarticular infections (OAIs) in children under 4years of age. Differentiation between K. kingae and Gram-positive cocci (GPC) is of great interest therapeutically. Objective: Our aim was to identify early distinguishing MRI features of OAIs. Materials and methods: Thirty-one children younger than 4years of age with OAI underwent MRI at presentation. Of these, 21 were caused by K. kingae and ten by GPC. Bone and soft tissue reaction, epiphyseal cartilage involvement, bone and subperiosteal abscess formation were compared between the two groups. Interobserver agreement was measured. Results: Bone reaction was less frequent (P = 0.0066) and soft tissue reaction less severe (P = 0.0087) in the K. kingae group. Epiphysis cartilage abscesses were present only in the K. kingae group (P = 0.0118). No difference was found for bone abscess (P = 0.1411), subperiosteal abscess (P = 1) or joint effusion (P = 0.4414). Interobserver agreement was good for all criteria. Conclusion: MRI is useful in differentiating K. kingae from GPC in OAI. Cartilaginous involvement and modest soft tissue and bone reaction suggest K. kingae
Databáze: OpenAIRE
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