Clinical presentation and treatment outcome of retinoblastoma in children of South Western China
| Autor: | Da-Nian Chen, Weimin He, Bo Guo, Jun Chen, Jing-Ge Gao, Jihong Zeng, Fang Lu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
retina chemotherapy 0302 clinical medicine Stage (cooking) Young adult Fluorescein Angiography Ultrasonography Doppler Color Child Incidence (epidemiology) Incidence General Medicine Prognosis Combined Modality Therapy Magnetic Resonance Imaging Survival Rate neoplasia 030220 oncology & carcinogenesis Child Preschool Female medicine.symptom enucleation Research Article Diagnostic Imaging medicine.medical_specialty China Adolescent Fundus Oculi Leukocoria Retinal Neoplasms Enucleation Observational Study survival retinoblastoma 03 medical and health sciences Young Adult Internal medicine medicine Humans Risk factor Retrospective Studies business.industry Proportional hazards model Infant Newborn Infant Retrospective cohort study South Western China Surgery 030221 ophthalmology & optometry business Tomography X-Ray Computed |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | To study the clinical presentation and treatment outcome among children in South Western China with retinoblastoma (RB) and to determine factors predictive of poor outcome. A retrospective review of children diagnosed with RB from 2006 to 2015 at West China Hospital was undertaken. Demographic and clinical characteristics and treatment outcomes were studied. A total of 253 patients (unilateral 80.2%, bilateral 19.8%) were studied. Twenty six patients (10.3%) were from minority ethnic groups of China. The median onset age was 21 months. Leukocoria was the most common presenting sign (71%). Tumors were intraocular in 91.3% cases, extraocular in 8.7% cases. Extraocular RB patients had a longer median lag period than intraocular patients (9 months vs 2 months, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|