Histopathology of tumors of the pineal region
| Autor: | Alexandre Vasiljevic, Anne Jouvet, Jacques Champier, Michelle Fèvre-Montange |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pineoblastoma
endocrine system Cancer Research Pathology medicine.medical_specialty Germinoma Brain Neoplasms business.industry Choriocarcinoma Pineocytoma General Medicine Neoplasms Germ Cell and Embryonal medicine.disease Pineal Gland Embryonal carcinoma Oncology medicine Humans Teratoma Germ cell tumors business Papillary tumors of the pineal region Pinealoma |
| Zdroj: | Future Oncology. 6:791-809 |
| ISSN: | 1744-8301 1479-6694 |
| DOI: | 10.2217/fon.10.28 |
| Popis: | Pineal region tumors are heterogeneous lesions and include mainly pineal parenchymal tumors (PPTs), papillary tumors of the pineal region (PTPRs) and germ cell tumors (GCTs). This article describes the cystic pineal gland compared with normal tissue and histopathological features of the most frequent pineal region tumors. PPTs are subdivided into pineocytoma (grade I), pineoblastoma (grade IV) and tumors with intermediate differentiation (PPTIDs; grades II–III). A grading system based on the number of mitoses and neurofilament protein expression distinguishes low- from high-grade PPTID. PTPR is a new tumoral entity thought to originate from the subcommissural organ. GCTs include germinoma, embryonal carcinoma, teratoma, yolk sac tumor and choriocarcinoma and are often of mixed histologic composition. New histogenetic data for GCTs are presented. |
| Databáze: | OpenAIRE |
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