Pharmacological activities of someArgyranthemum species growing in the Canary Islands

Autor: R. B. Badisa, Maria Couladis, E. Pilarinou, V. Tsortanidou, J. Francisco-Ortega, Larry A. Walker, A. Santos-Guerra, S. K. Chaudhuri
Rok vydání: 2004
Předmět:
Zdroj: Phytotherapy Research. 18:763-767
ISSN: 1099-1573
0951-418X
DOI: 10.1002/ptr.1530
Popis: Methanolic extracts of eight subspecies of genus Argyranthemum were evaluated against brine shrimps, human cancer cell lines, malarial parasites and microorganisms under in vitro conditions. In the shrimp assay, samples of A. adauctum ssp. adauctum, A. adauctum ssp. erythrocarpon and A. frutetescens ssp. succulentum were active with ED50 values in the range of around 300 to 360 µg/ml. In the Caco-2, HepG2 and MCF-7 cell lines, the samples A. adauctum ssp. jacobaeifolium and A. adauctum ssp. palmensis were active with LC50 values ranging between 80–90 µg/ml. The secondary assay results of antimalarial activity of samples, A. adauctum ssp. adauctum, A. adauctum ssp. dugourii, A. adauctum ssp. erythrocarpon and A. adauctum ssp. jacobaeifolium have IC50 values
Databáze: OpenAIRE