Effects of aging on neuroendocrine activation in subjects and patients in the presence and absence of heart failure with left ventricular systolic dysfunction

Autor: Susan Ward, M. Impallomeni, Celia M. Oakley, David P. Dutka, John G.F. Cleland, Iacopo Olivotto
Rok vydání: 1996
Předmět:
Zdroj: The American journal of cardiology. 77(14)
ISSN: 0002-9149
Popis: The neuroendocrine profile and echocardiographic features of 40 patients (81 +/- 1 years, means +/- standard error) with heart failure and impaired left ventricular systolic function were compared with those of an age-matched group of healthy subjects, 20 younger patients with heart failure (aged 58 +/- 1 years) and 15 younger healthy subjects. Normal elderly subjects had a neuroendocrine profile similar to that of healthy younger subjects apart from elevated plasma norepinephrine (958 +/- 84 vs 302 +/- 118 pg/ml; p< 0.001) and atrial natriuretic peptide ( 40 +/- 6 vs 28 +/- 5 pg/ml; p
Databáze: OpenAIRE