Impaired regulation of calcium excretion in kidney transplant recipients
Autor: | Ruzica Smalcelj, Vesna Kušec |
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Rok vydání: | 2011 |
Předmět: |
Adult
Male medicine.medical_specialty Metabolic Clearance Rate chemistry.chemical_element Renal function Calcium Kidney Function Tests Collagen Type I Phosphates chemistry.chemical_compound Postoperative Complications calcium kidney transplant N-terminal telopeptide Internal medicine medicine Humans Kidney transplantation Aged Calcifediol Aged 80 and over Calcium metabolism Kidney Hyperparathyroidism Creatinine business.industry General Medicine Middle Aged Alkaline Phosphatase medicine.disease Kidney Transplantation medicine.anatomical_structure Endocrinology chemistry Parathyroid Hormone Hypercalcemia Female Peptides business Receptors Calcium-Sensing |
Zdroj: | Wiener klinische Wochenschrift. 123:334-339 |
ISSN: | 1613-7671 0043-5325 |
DOI: | 10.1007/s00508-011-1575-6 |
Popis: | Disorders of mineral metabolism and hypercalcemia are frequent in kidney transplant recipients. Calcium to creatinine (Ca/Cr) clearance ratio was used as a criterion to distinguish between different calcium metabolism disorders. The study comprised 91 (53 men, 38 women) kidney recipients aged 23–70 years, with creatinine clearance (CrCl) >60 ml/min. The following parameters related to mineral metabolism were measured in serum: iPTH, total alkaline phosphatase (tALP), telopeptide (bone degradation marker, CTX), 25(OH)D3, total and ionized calcium, Ca++ , Pi, creatinine (Cr). Creatinine and Ca were also determined in urine, as well as Ca/Cr clearance ratio. According to the Ca/Cr clearance ratio, patients were divided into three groups as follows: 0.02 (found in hyperparathyroidism, N = 16). In the group of patients with Ca/Cr clearance ratio |
Databáze: | OpenAIRE |
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