Impaired regulation of calcium excretion in kidney transplant recipients

Autor: Ruzica Smalcelj, Vesna Kušec
Rok vydání: 2011
Předmět:
Zdroj: Wiener klinische Wochenschrift. 123:334-339
ISSN: 1613-7671
0043-5325
DOI: 10.1007/s00508-011-1575-6
Popis: Disorders of mineral metabolism and hypercalcemia are frequent in kidney transplant recipients. Calcium to creatinine (Ca/Cr) clearance ratio was used as a criterion to distinguish between different calcium metabolism disorders. The study comprised 91 (53 men, 38 women) kidney recipients aged 23–70 years, with creatinine clearance (CrCl) >60 ml/min. The following parameters related to mineral metabolism were measured in serum: iPTH, total alkaline phosphatase (tALP), telopeptide (bone degradation marker, CTX), 25(OH)D3, total and ionized calcium, Ca++ , Pi, creatinine (Cr). Creatinine and Ca were also determined in urine, as well as Ca/Cr clearance ratio. According to the Ca/Cr clearance ratio, patients were divided into three groups as follows: 0.02 (found in hyperparathyroidism, N = 16). In the group of patients with Ca/Cr clearance ratio
Databáze: OpenAIRE