Efficacy of Multipurpose Contact Lens Solutions Against ESBL-Positive Escherichia coli, MRSA, and Candida albicans Clinical Isolates
| Autor: | Müge Demirbilek, Ebru Evren |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Methicillin-Resistant Staphylococcus aureus
biology Colony Count Microbial Microbial Sensitivity Tests Antimicrobial biology.organism_classification medicine.disease_cause Corpus albicans Incubation period Microbiology Disinfection Ophthalmology Contact lens solutions Anti-Infective Agents Staphylococcus aureus Candida albicans Escherichia coli medicine Contact Lens Solutions Bacteria |
| Zdroj: | Eye & Contact Lens: Science & Clinical Practice. 40:157-160 |
| ISSN: | 1542-2321 |
| Popis: | OBJECTIVES The antimicrobial effects of multipurpose contact lens solutions (MPSs) have been evaluated according to ISO 14729 standards. The aim of this study was to assess the efficacy of commercially available MPSs against extended-spectrum beta lactamases (ESBL)-producing Escherichia coli, methicillin-resistant Staphylococcus aureus (MRSA), and Candida albicans clinical isolates. METHODS Three commercially available contact lens solutions (Opti-Free Expresss, ReNu MultiPlus, and Solo Care Aqua) were tested against 18 ESBL-positive E. coli clinical strains, 20 MRSA clinical strains, and 20 C. albicans clinical strains. The stand-alone assays for bacteria and fungi were performed according to ISO 14729 criteria, and all samples were evaluated after 2, 4, and 24 hours of incubation. The numbers of viable microorganisms were evaluated by the plate-counting method. RESULTS All MPSs demonstrated at least 3 log reduction in colony-forming units (CFU) for all bacterial isolates and 1 log reduction in CFU for all yeast isolates, which meets ISO 14729 standards. Although no statistically significant differences were obtained among MPSs for bacterial isolates, variable responses were observed against clinical isolates: 5% povidone-iodine was more effective compared with Solo Care Aqua for C. albicans clinical strains (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|