CEREBROVASCULAR COMPLICATIONS OF L-ASPARAGINASE THERAPY IN CHILDREN WITH LEUKEMIA - APHASIA AND OTHER NEUROPSYCHOLOGICAL DEFICITS
| Autor: | Willem Kamps, R. Le Coultre, Rienk Y. J. Tamminga, Annette Kingma, R. J. Saan |
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| Přispěvatelé: | Faculteit Medische Wetenschappen/UMCG |
| Jazyk: | angličtina |
| Rok vydání: | 1993 |
| Předmět: |
Male
Coagulation protein Pediatrics medicine.medical_specialty Adolescent Lymphoblastic Leukemia CHILDHOOD Neuropsychological Tests CEREBROVASCULAR ACCIDENT APHASIA IN CHILDREN L-ASPARAGINASE L asparaginase NEUROPSYCHOLOGICAL DEFICITS Aphasia medicine Asparaginase Humans Child business.industry ACUTE LYMPHOBLASTIC LEUKEMIA Neuropsychology Hematology Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Surgery Cerebrovascular Disorders Leukemia Cerebral thrombosis Oncology Pediatrics Perinatology and Child Health Female medicine.symptom business |
| Zdroj: | Pediatric hematology and oncology, 10(4), 303-309. TAYLOR & FRANCIS INC |
| ISSN: | 0888-0018 |
| Popis: | Children with acute lymphoblastic leukemia (ALL), treated with L-asparaginase are at risk for cerebral thrombosis or hemorrhage because of coagulation protein deficiencies. The results and the importance of serial neuropsychological examinations after such complications in three children with ALL are presented. All patients showed marked aphasia and other cognitive deficits. Recovery was complete in two of three children. |
| Databáze: | OpenAIRE |
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