Predictive value of platelet-to-lymphocyte ratio in exacerbation of chronic obstructive pulmonary disease
Autor: | Gülistan Karadeniz, Onur Fevzi Erer, Kübra Sonat, Serir Aktogu, Serpil Bulaç Kir, Melike Demir, Sibel Doruk |
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Rok vydání: | 2016 |
Předmět: |
Blood Platelets
Male medicine.medical_specialty Pathology Exacerbation Lymphocyte Clinical Biochemistry Pulmonary disease Inflammation 030204 cardiovascular system & hematology 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Predictive Value of Tests Internal medicine Forced Expiratory Volume Drug Discovery medicine Humans Platelet Lymphocytes Mean platelet volume Aged COPD business.industry Biochemistry (medical) Platelet Distribution Width Smoking Middle Aged medicine.disease respiratory tract diseases body regions medicine.anatomical_structure C-Reactive Protein 030228 respiratory system ROC Curve Area Under Curve Case-Control Studies Cardiology Disease Progression Female medicine.symptom business Mean Platelet Volume |
Zdroj: | Biomarkers in medicine. 10(7) |
ISSN: | 1752-0371 |
Popis: | Aim: We aimed to assess the platelet-to-lymphocyte ratio (PLR) and platelet parameters in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 60 stable COPD patients, 50 acute exacerbation COPD patients and 50 healthy controls were enrolled in this study. Results: The platelet distribution width and PLR were higher and the mean platelet volume was lower in the COPD patients during acute exacerbation compared with the stable patients and controls. The PLR was negatively correlated with the forced expiratory volume in 1 s. Conclusion: The PLR may be used as a useful and easily accessible tool for evaluating the ongoing inflammation during stable period and the disease severity during acute exacerbations in COPD patients. |
Databáze: | OpenAIRE |
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