Stenting deferral in primary percutaneous coronary intervention: exploring benefits and suitable interval in heavy thrombus burden
| Autor: | Hosam Hasan-Ali, Salwa R. Demitry, Mohamed Zaky, Ahmed Magdy, Mohamed Abd El-Hady, Mohamed Abdel Ghany |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Slow-flow medicine.medical_treatment ST-segment elevation No-reflow Group B law.invention Randomized controlled trial law Internal medicine medicine Diseases of the circulatory (Cardiovascular) system Myocardial infarction cardiovascular diseases Thrombus business.industry Percutaneous coronary intervention Stent medicine.disease surgical procedures operative RC666-701 Cardiology business Deferral Mace TIMI |
| Zdroj: | The Egyptian Heart Journal, Vol 73, Iss 1, Pp 1-9 (2021) |
| Popis: | Background Deferred stenting, despite being successful in early studies, showed no benefit in recent trials. However, these trials were testing routine deferral; not in patients with heavy thrombus burden. Results This is a prospective, Randomized Clinical Trial that included 150 patients who presented with STEMI, patients were allocated into three equal groups after the coronary angiography ± primary intervention and before stenting of the culprit lesion; group (A) included 50 patients with early deferral of stenting, group (B) included 50 patients with late deferral and group (C) included 50 patients with immediate stenting. No-reflow was significantly higher in group C, while Final TIMI flow grade 3 and MBG grade 3 were significantly higher in group A and B than group C; p = 0.019 and p p = 0.029). Conclusions Stent deferral was proved to be better than immediate stenting after recanalization of IRA, in achieving TIMI III flow, reducing risk of 6 months MACE, and restoration of myocardial function in a subset of STEMI patients presenting with large thrombus burden. While, no significant difference was found between both deferral times in final TIMI flow, or clinical outcomes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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