Citogenetička istraživanja radnika Srbije profesionalno izloženih pesticidima
| Autor: | Ljiljana Radivojevic, Vaskrsije Janjic, Boban Rakic, Dubravka Jovicic, Jelena Pajic, Aleksandar Milovanović, Milos Pajic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
lcsh:QH426-470
Population Plant Science Biology Toxicology 03 medical and health sciences 0302 clinical medicine Human lymphocytes Biomonitoring chromosomal aberrations Genetics Correlation test education Continuous exposure 030304 developmental biology 0303 health sciences education.field_of_study occupational exposure pesticides Pesticide Control subjects 3. Good health lcsh:Genetics 030220 oncology & carcinogenesis Occupational exposure Linear correlation |
| Zdroj: | Genetika, Vol 45, Iss 1, Pp 121-133 (2013) Genetika |
| ISSN: | 1820-6069 0534-0012 |
| Popis: | The aim of this study was the analysis of chromosomal aberrations (CA) and premature centromeric division (PCD) in people exposed to pesticides at work. The research included 26 subjects occupationally exposed to pesticides, of average age 39.89 + 8.66, and 32 control subjects of average age 40.57 + 6.57. Mann-Whitney U tests showed statistically significant differences between the groups for mean values of all the examined variables. In addition, Spearman's (non-parametric) correlation test detected a positive linear correlation between CA and PCD. The presence of mostly chromatid and isochromatid breaks in the examinees indicates continuous exposure to pesticides. The absence of complex chromosomal rearrangements points to adequate protection of the subjects at their work places. Cilj istraživanja bila je analiza hromozomskih aberacija (CA) i prevremene centromerne deobe (PCD) kod lica profesionalno izloženih pesticidima. Istraživanja su obuhvatala 26 ispitanika profesionalno izloženi pesticidima prosečne starosti 39.89+ 8.66 i 32 ispitanika kontrolne grupe prsečne starosti 40.57+ 6.57. Mann-Whitney U test pokazuje statistički značajnu razliku srednjih vrednosti parametara svih ispitivanih varijabli u odnosu na kontrolnu grupu. Osim toga, Spearmanova (neparametarska) korelacija je pokazala da postoji pozitivna linearna korelacija između CA i PCD. Prisustvo uglavnom hromatidnih i izohromatidnih prekida kod ispitanika ukazuju na kontinuirano izlaganje pesticidima. Odsustvo složenih hromozomskih rearanžmana ukazuje na dobru zaštitu ispitanika na njihovim radnim mestima. |
| Databáze: | OpenAIRE |
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