Prevalence of pain and treatment outcomes among cancer patients in a Malaysian palliative care unit

Autor: Morna Chua, Jerry Liew, Ilmiyah Che Wan, Jacqueline Lai, Syuhaidah Abdul Rahman, Thamron Keowmani, Melissa Mejin
Rok vydání: 2019
Předmět:
Palliative care
Treatment outcome
lcsh:RS1-441
Pharmaceutical Science
Pharmacy
030226 pharmacology & pharmacy
Analgesics Non-Narcotic
0302 clinical medicine
mesh:Pain
Prevalence
Medicine
mesh:Analgesics
mesh:Patient Reported Outcome Measures
Original Research
Pain Measurement
mesh:Palliative Care
Terminal Care
Analgesics
Palliative Care
Treatment Outcome
mesh:Treatment Outcome
medicine.drug
medicine.medical_specialty
mesh:Terminal Care
Analgesic
Pain
Opioid
mesh:Pain Measurement
lcsh:Pharmacy and materia medica
03 medical and health sciences
Rating scale
Internal medicine
mesh:Pain Management
Non-Narcotic
Pain Management
mesh:Opioid
Patient Reported Outcome Measures
mesh:Malaysia
business.industry
lcsh:RM1-950
Malaysia
Cancer
Pain management
medicine.disease
lcsh:Therapeutics. Pharmacology
mesh:Non-Narcotic
Analgesics Opioid
business
Patient education
Zdroj: Pharmacy Practice (Granada), Volume: 17, Issue: 1, Article number: 1397, Published: 11 NOV 2019
Pharmacy Practice, Vol 17, Iss 1, p 1397 (2019)
Pharmacy Practice (Granada) v.17 n.1 2019
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice
ISSN: 1886-3655
1885-642X
DOI: 10.18549/pharmpract.2019.1.1397
Popis: Background: Pain remains one of the most common and debilitating symptoms of advanced cancer. To date, there is a lack of studies on pain and its treatment among Malaysian palliative care patients. Objective: This study aimed to explore the prevalence of pain and its treatment outcomes among adult cancer patients admitted to a palliative care unit in Sabah, Malaysia. Methods: Of 327 patients screened (01/09/15-31/12/17), 151 patients with assessed self-reported pain scores based on the numerical rating scale of 0-10 (current, worst and least pain within the past 24 hours) upon admission (baseline), 24, 48 and 72 hours post-admission and discharge were included. Pain severity and pain score reductions were analysed among those who experienced pain upon admission or in the past 24 hours. Treatment adequacy was measured by the Pain Management Index (PMI) among discharged patients. The PMI was constructed upon worst scores categorised as 0 (no pain), 1 (1-4, mild pain), 2 (5-6, moderate pain), or 3 (7-10, severe pain) which is then subtracted from the most potent level of prescribed analgesic drug scored as 0 (no analgesia), 1 (non-opioid), 2 (weak opioid) or 3 (strong opioid). PMI≥0 indicated adequate treatment. Results: Upon admission, 61.1% [95%CI 0.54:0.69] of 151 patients presented with pain. Of 123 patients who experienced pain upon admission or in the past 24 hours, 82.1% had moderate to severe worst pain. Throughout patients’ ward stay until discharge, there was an increased prescribing of analgesics and adjuvants compared to baseline, excluding weak opioids, with strong opioids as the mainstay treatment. For all pain score types (current, worst and least pain within the past 24 hours), means decreased at each time point (24, 48 and 72 hours post-admission and discharge) from baseline, with a significant decrease at 24 hours post-admission (p
Databáze: OpenAIRE