Origin of some enkephalin-containing afferents to the ventro-medial region of the globus pallidus in the rat

Autor: François Cesselin, Michel Arluison, Myriana Vankova, Vincent Leviel
Rok vydání: 1990
Předmět:
Zdroj: Brain Research Bulletin. 25:25-34
ISSN: 0361-9230
DOI: 10.1016/0361-9230(90)90249-y
Popis: The retrograde transport of WGA-HRP adsorbed to colloidal gold was combined with the indirect immunoperoxidase technique to study the origin of enkephalin-containing afferents to the medial and ventral regions of the globus pallidus (GP). On the injected side, the nerve cell bodies labeled retrogradely or double labeled were numerous in the central nucleus of the amygdala (ACe), scattered in the bed nucleus stria terminalis (BNST) and few in the fundus striati. In the ACe, approximately 40% and 20% of the retrogradely labeled perikarya were found immunoreactive for Met-enkephalin and Leu-enkephalin, respectively, whereas they were only 30% and 15% in the BNST. It is concluded that the enkephalinergic afferents of the ventro-medial region of GP, which contains the basal nucleus of Meynert in the rat, are largely of limbic origin.
Databáze: OpenAIRE