Infections of the spinal subdural space in children: a series of 11 contemporary cases and review of all published reports. A multinational collaborative effort
| Autor: | Erwin M. J. Cornips, Rick Abbott, Lawrence B. Daniels, Rahul Gupta, Mostafa El Khashab, Adam L. Sandler, Sandeep Mohindra, Dominic Thompson, Farideh Nejat, Reza Yassari, Arundhati Biswas, Eliezer Kolatch, James T. Goodrich, Jasper van Aalst |
|---|---|
| Přispěvatelé: | RS: MHeNs School for Mental Health and Neuroscience, MUMC+: MA Med Staf Spec Neurochirurgie (9), Neurochirurgie |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent International Cooperation MEDLINE Central nervous system Disease Subdural Space Spinal subdural infection Spinal Cord Diseases Spinal intradural abscess Young Adult Medicine Humans Cyst Meningitis Young adult Abscess Child Spinal subdural abscess Children business.industry Infant General Medicine medicine.disease Empyema Surgery medicine.anatomical_structure Spinal Cord Child Preschool Pediatrics Perinatology and Child Health Africa Female Neurology (clinical) Neurosurgery Presentation (obstetrics) business |
| Zdroj: | Child's Nervous System, 29(1), 105-117. Springer |
| ISSN: | 1433-0350 0256-7040 |
| Popis: | Positioned anatomically between the spinal epidural space and the intramedullary compartment, the spinal subdural space remains the least common area of localized infection in the central nervous system. Infectious processes of the subdural spinal space include subdural spinal empyema, subdural spinal abscess, infected spinal subdural cyst, and infectious spinal subdural cyst. To date, there has been no systematic review of these entities in children, with the cumulative knowledge of the pathophysiologic, microbiologic, and demographic characteristics of these infections relegated solely to few small series and case reports. A series of 11 recent cases culled from the collaboration of international authors are presented. In addition, an exhaustive MEDLINE search and manual review of the international literature was performed, identifying a total of 73 cases of spinal subdural infections in patients under the age of 21. Data of interest include the age, sex, signs, and symptoms at presentation, spinal location of infection, presence of spinal dysraphism, and other comorbidities, offending organism, treatment, outcome, and follow-up. Patients ages ranged from 4 weeks to 20 years (mean, 6.5 years). Males outnumbered females by a ratio of 2:1. Over half (53 %) of spinal subdural infections in children were associated with spinal dysraphism or other congenital abnormalities of the spine. The commonest organism to infect the spinal subdural space in children is mycobacterium tuberculosis and the thoracic spinal region was most commonly infected. The disease is usually treated surgically, although a more expectant approach consisting of antibiotics and observation has also been proposed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink