HTLV-I infection in patients with autoimmune thyroiditis (Hashimoto's thyroiditis)
| Autor: | Setsuko Kashiwagi, Shiro Saito, Masaru Iwasa, Kenjiro Masuda, Hisaomi Kawai, Tomohiko Inui, Akira Kondo, S. Niki, Takayuki Tsuchihashi |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male endocrine system endocrine system diseases viruses Population Thyroiditis Autoimmune thyroiditis Myelopathy Japan immune system diseases Virology Immunopathology Tropical spastic paraparesis medicine Humans education Aged Autoimmune disease Aged 80 and over education.field_of_study business.industry Thyroiditis Autoimmune virus diseases Middle Aged medicine.disease HTLV-I Infections Paraparesis Tropical Spastic HTLV-I Antibodies Infectious Diseases Immunology Female Viral disease business Epidemiologic Methods |
| Zdroj: | Journal of medical virology. 38(2) |
| ISSN: | 0146-6615 |
| Popis: | To investigate the possible relationship of HTLV-I virus infection to autoimmune thyroid disease, we examined, firstly, the frequency of HTLV-I seropositivity among patients with Hashimoto's thyroiditis and, secondly, the frequency of Hashimoto's thyroiditis in patients with HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP). Of 144 patients with Hashimoto's thyroiditis in the Tokushima and Kochi Prefectures, Japan, 9 (6.3%) were positive for serum HTLV-I virus antibody 2 of whom were confirmed histologically to have Hashimoto's thyroiditis. This percentage is significantly higher (P < 0.01) than the estimated prevalence (2.2%) of HTLV-I carriers among the general population in this region. Of 9 patients with HAM/TSP, 3 (33.3%), including 2 biopsy-proven cases, had evidence of Hashimoto's thyroiditis. This proportion is apparently much higher than the prevalence (1.7%) of Hashimoto's thyroiditis in the general population. These findings suggest that HTLV-I virus may be related to the development of Hashimoto's thyroiditis. © 1992 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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