Face processing of social cognition in patients with first episode psychosis: Its deficits and association with the right subcallosal anterior cingulate cortex
| Autor: | Marina Mihaljevic, Semra Etyemez, F. C. Nucifora, Andreia V. Faria, Hironori Kuga, Ho Namkung, Jeffrey L. Crawford, Peeraya Piancharoen, Jennifer M. Coughlin, Koko Ishizuka, Kun Yang, Rebecca Schaub, Jun Miyata, Thomas W. Sedlak, Zui Narita, Luisa Longo, Akira Sawa, David J. Schretlen, Gerald Nestadt |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Social Cognition
Psychosis medicine.medical_specialty Functional connectivity Audiology medicine.disease Gyrus Cinguli Magnetic Resonance Imaging Psychiatry and Mental health medicine.anatomical_structure Psychotic Disorders Social cognition First episode psychosis Brain size medicine Humans In patient Association (psychology) Psychology Facial Recognition Biological Psychiatry Anterior cingulate cortex |
| Zdroj: | Schizophrenia research. 238 |
| ISSN: | 1573-2509 |
| Popis: | The clinical importance of social cognition is well acknowledged in patients with psychosis, in particular those with first episode psychosis (FEP). Nevertheless, its brain substrates and circuitries remain elusive, lacking precise analysis between multimodal brain characteristics and behavioral sub-dimensions within social cognition. In the present study, we examined face processing of social cognition in 79 FEP patients and 80 healthy controls (HCs). We looked for a possible correlation between face processing and multimodal MRI characteristics such as resting-state functional connectivity (rsFC) and brain volume. We observed worse recognition accuracy, longer recognition response time, and longer memory response time in FEP patients when compared with HCs. Of these, memory response time was selectively correlated with specific rsFCs, which included the right subcallosal sub-region of BA24 in the ACC (scACC), only in FEP patients. The volume of this region was also correlated with memory response time in FEP patients. The scACC is functionally and structurally important in FEP-associated abnormalities of face processing measures in social cognition. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect