The risk of ectopic pregnancy following tubal reconstructive microsurgery and assisted reproductive technology procedures
| Autor: | Peter Hillemanns, Cordula Schippert, Philipp Soergel, Guillermo-José Garcia-Rocha, Christina Bassler, Susanne Gagalick, Ismini Staboulidou, Klaus Buehler |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Risk Infertility Microsurgery medicine.medical_specialty animal structures Reproductive Techniques Assisted medicine.medical_treatment Population Reproductive technology Young Adult Gynecologic Surgical Procedures Pregnancy medicine Humans education Fallopian Tubes Salpingitis isthmica nodosa Retrospective Studies Gynecology education.field_of_study Assisted reproductive technology Ectopic pregnancy Obstetrics business.industry Incidence Smoking Obstetrics and Gynecology Salpingitis General Medicine Fallopian Tube Diseases medicine.disease female genital diseases and pregnancy complications Pregnancy Ectopic Female Sterilization Reversal business Infertility Female |
| Zdroj: | Archives of Gynecology and Obstetrics. 285:863-871 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-011-2092-6 |
| Popis: | The incidence of ectopic pregnancy (EP) in the general population is 2%, whereas the EP rate following assisted reproductive technologies (ART) is between 2.1 and 11%. EP is also an adverse effect of tubal surgery with incidences up to 40% depending on the type, location, and severity of tubal disease and the surgical procedure. This paper looks at the incidence of EP following tubal reconstructive microsurgery, analyzes risk factors for EP following own 1,295 ART cycles and looks on the incidence of EP in 128,314 pregnancies following ART according to the presence or absence of tubal infertility using data from the German IVF Registry (DIR). In our clinic, the EP rate following resterilization was 6.7%. In the presence of acquired tubal disease, the EP rate following adhesiolysis, salpingostomy, salpingoneostomy, fimbrioplasty, and anastomosis was 7.9%. The EP rate following ART in our clinic was 5.6%. Previous abdominal surgeries, microsurgical procedures, hydro-/sactosalpinges, salpingitis, salpingitis isthmica nodosa, and periadnexal adhesions showed a significant positive correlation with EP as outcome. Data of DIR demonstrate a significantly increased incidence of EP in the presence of tubal pathology. The highest EP rate related to all clinical pregnancies was 4.5% (95% CI 3.0–6.0) in smoking women |
| Databáze: | OpenAIRE |
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