Chronic stress effects on the rat adrenal cortex
| Autor: | Josiane Vivier, Maria C. Magalhães, G. Defaye, Ana Rita Castro, Duarte Pignatelli, Marta Maia |
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| Předmět: |
medicine.medical_specialty
Adrenocorticotropic hormone Plasma renin activity chemistry.chemical_compound Endocrinology Adrenocorticotropic Hormone Corticosterone Reference Values Stress Physiological Internal medicine Renin–angiotensin system Renin Medicine Animals Chronic stress ACTH receptor Rats Wistar Aldosterone business.industry Adrenal cortex General Medicine Rats medicine.anatomical_structure chemistry Receptors Corticotropin Chronic Disease Adrenal Cortex business Receptor Melanocortin Type 2 |
| Zdroj: | CIÊNCIAVITAE Scopus-Elsevier |
| Popis: | Under the influence of a chronic permanent stress, the adrenal function as well as the entire hypothalamic-pituitary-adrenal axis (HPAA) suffered an adaptation process that resulted in the normalization of the studied stress hormones (ACTH, corticosterone and aldosterone) with the exception of plasma renin activity which first diminished and at the end increased. ACTH receptors exhibited a dual response since after 14 days of permanent stress MC2-R showed a slight reduction while MC5-R was still up-regulated. |
| Databáze: | OpenAIRE |
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