Hospital-based Diagnosis of Hemorrhagic Fever, Encephalitis, and Hepatitis in Cambodian Children
| Autor: | Rathavuth Hong, Touch Sok, Yuvatha Kdan, Ananda Nisalak, Kyi Minn, Khin Saw Aye Myint, Timothy P. Endy, Gaye Ruble, Y. Meng Chhour, David W. Vaughn |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Microbiology (medical)
Pediatrics medicine.medical_specialty Hemorrhagic Fevers Viral Adolescent Epidemiology viruses lcsh:Medicine Dengue virus medicine.disease_cause Polymerase Chain Reaction Dengue fever lcsh:Infectious and parasitic diseases medicine Prevalence Humans hepatitis lcsh:RC109-216 Serotyping Child Hepatitis B virus Hepatitis business.industry Research lcsh:R Hepatitis A Infant Hepatitis C Japanese encephalitis medicine.disease Virology dengue Southeast Asia Hospitals Infectious Diseases Child Preschool Population Surveillance surveillance Encephalitis business Cambodia hemorrhagic fever |
| Zdroj: | Emerging Infectious Diseases, Vol 8, Iss 5, Pp 485-489 (2002) Emerging Infectious Diseases |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | Surveillance was conducted for three clinical syndromes (hemorrhagic fever, encephalitis, and hepatitis) in Cambodian children admitted to the National Pediatric Hospital in Phnom Penh from July 1996 through September 1998. Acute- and convalescent-phase sera, and cerebrospinal fluid, when applicable, underwent diagnostic evaluation for infections with Dengue virus (DENV), Japanese encephalitis virus (JEV), and Hepatitis A, B, C, and E viruses. Of 621 children admitted with hemorrhagic fever, 499 (80%) were confirmed to have either primary or secondary DENV infection. DENV rates were as high as 10.6/100 hospital admissions in September 1998. Of 50 children with clinical encephalitis, 9 (18%) had serologic evidence of JEV infection. Forty-four children had clinical hepatitis, most (55%) due to Hepatitis A virus (HAV). One patient had Hepatitis B virus, and no patients had hepatitis C or E. This study identified a large number of children with vaccine-preventable diseases (JEV and HAV). |
| Databáze: | OpenAIRE |
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