Efficacy of a 0.15% benzydamine hydrochloride and 0.05% cetylpyridinium chloride mouth-rinse on 4-day de novo plaque formation
| Autor: | David Herrera, Mariano Sanz, Sagrario Santos, Germán Barbieri, Leonardo Trombelli, Jorge Ferrus |
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| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Benzydamine Adolescent Anti-Inflammatory Agents Dental Plaque Mouthwashes Dentistry Cetylpyridinium macromolecular substances Dental plaque Placebo Cetylpyridinium chloride Oral hygiene chemistry.chemical_compound medicine Humans Analysis of Variance Cross-Over Studies business.industry Dental Plaque Index technology industry and agriculture medicine.disease Crossover study Drug Combinations chemistry Anti-Infective Agents Local Periodontics Female Periodontal Index business medicine.drug |
| Popis: | Objective: To evaluate the effect of a mouth-rinse formulation combining benzydamine hydrochloride and cetylpyridinium chloride (BNZ+CPC) in preventing de novo plaque formation, in comparison with CPC and placebo mouth rinses. Patients and Methods: This was a controlled, observer-blind, cross-over study. In this model of plaque re-growth, subjects received a session of oral prophylaxis and were directed to withdraw oral hygiene measures for the next 4 days, using only the mouth rinse assigned. The outcome parameters were the plaque index (PII) and gingival index (GI). In addition, microbiological evaluation of the subgingival microflora, by means of culture, was performed, as well as patient-based variables. Data analysis was carried out using ANOVA for Latin-square design. Results: The analysis of variance showed a significant statistical difference between the BNZ+CPC association and placebo (p |
| Databáze: | OpenAIRE |
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