Hyperferritinaemia following intrauterine transfusions for Rh isoimmunisation
| Autor: | Rajendra Prasad Anne, Venkataseshan Sundaram, Praveen Kumar, Sourabh Dutta |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
0301 basic medicine Middle Cerebral Artery medicine.medical_specialty Iron Overload Blood Transfusion Intrauterine 030105 genetics & heredity Rh Isoimmunization Antiviral Agents 03 medical and health sciences 0302 clinical medicine Rh isoimmunisation Cholestasis Pregnancy medicine.artery medicine Humans Valganciclovir Adverse effect Intrauterine transfusion Fetus Unusual Presentation of More Common Disease/Injury Obstetrics business.industry Pregnancy Complications Hematologic Infant Newborn Clinical course Bilirubin General Medicine Phototherapy medicine.disease Failure to Thrive Unconjugated bilirubin Treatment Outcome Ferritins Middle cerebral artery Female business Blood Flow Velocity 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2018-227225 |
| Popis: | Intrauterine transfusion is one of the mainstays of treatment in isoimmunised pregnancies guided by the changes in middle cerebral artery Doppler of the fetus. The common postnatal complications associated with Rh isoimmunisation are high unconjugated bilirubin requiring blood exchange transfusions, cholestasis due to bile inspissation, thrombocytopenia and anaemia. Hyperferritinaemia is an uncommon adverse effect observed in Rh isoimmunised pregnancies. In this case report, we describe the clinical course of a Rh isoimmunised neonate with hyperferritinaemia and transfusion acquired cytomegalovirus disease which resolved. Iron chelation therapy was not necessary. |
| Databáze: | OpenAIRE |
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