Differences in the Clinical Characteristics of Persistent Idiopathic Facial Pain (Atypical Odontalgia) Patients with or Without Neurovascular Compression of the Trigeminal Nerve

Autor: Shiori Sugawara, Norio Yoshino, Takayuki Suga, Miho Takenoshita, Takeshi Watanabe, Satoshi Takada, Trang T H Tu, Tohru Kurabayashi, Kaoru Kawasaki, Chaoli Hong, Akira Toyofuku, Lou Mikuzuki, Junichiro Sakamoto, Kazuya Watanabe
Rok vydání: 2020
Předmět:
Male
HEADACHE & FACIAL PAIN SECTION
Bipolar Disorder
Neurovascular Compression (NVC)
Facial Neuralgia
0302 clinical medicine
Trigeminal neuralgia
Medicine
Persistent Idiopathic Facial Pain (PIFP)
Original Research Article
030212 general & internal medicine
Somatoform Disorders
medicine.diagnostic_test
Catastrophization
Mental Disorders
Headache
General Medicine
Middle Aged
Functional Somatic Symptom
Anxiety Disorders
Magnetic Resonance Imaging
Neuropathic pain
Female
Pain catastrophizing
medicine.symptom
Chest Pain
medicine.medical_specialty
03 medical and health sciences
Toothache
Humans
Trigeminal Nerve
Retrospective Studies
Atypical Odontalgia (AO)
Neuropathic Pain
Trigeminal nerve
Depressive Disorder
business.industry
Nerve Compression Syndromes
Magnetic resonance imaging
medicine.disease
Dermatology
Dyspnea
Anesthesiology and Pain Medicine
Case-Control Studies
International Classification of Headache Disorders
Neurology (clinical)
business
Somatization
030217 neurology & neurosurgery
Zdroj: Pain Medicine: The Official Journal of the American Academy of Pain Medicine
ISSN: 1526-4637
1526-2375
DOI: 10.1093/pm/pnz300
Popis: Background Persistent idiopathic facial pain (PIFP) is the unexplained pain along the territory of the trigeminal nerve, including nonorganic tooth pain called atypical odontalgia (AO). Though PIFP is debilitating to patients’ livelihood and well-being, its pathophysiology remains poorly understood. Although neurovascular compression (NVC) of the trigeminal nerve is known to be associated with trigeminal neuralgia (TN), the relationship between NVC and other orofacial pains has not been fully elucidated. Methods In this study, we investigated the differences in the characteristics of PIFP (primarily AO) patients in the presence or absence of NVC. A retrospective analysis was performed on data from 121 consecutive patients who had been diagnosed with unilateral PIFP according to the criteria of the International Classification of Headache Disorders (ICHD)–3 and underwent magnetic resonance imaging scans of the head. Results In the group without NVC, characteristic findings were significant for psychiatric morbidity, somatization, and pain disability, when compared with the group with NVC. Furthermore, the group without NVC exhibited significant headache, noncardiac chest pain, shortness of breath, and pain catastrophizing. Conclusions These results suggest that PIFP patients can be divided into two groups: one consistent with a neuropathic pain phenotype when NVC is present and a functional somatic symptom phenotype when presenting without NVC. Our findings may enable a more precise understanding of pathophysiology of PIFP and lead to better treatment strategies.
Databáze: OpenAIRE
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