Evaluating the longitudinal effect of colorectal surgery on health-related quality of life in patients with colorectal cancer
| Autor: | Charlotte J L Molenaar, Loes Janssen, Cynthia S Bonhof, Floortje Mols, Gerrit D. Slooter, Muriël Reudink |
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| Přispěvatelé: | Medical and Clinical Psychology |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Adult
Male medicine.medical_specialty RESECTION Colorectal cancer Colon IMPACT Population EUROPEAN-ORGANIZATION QUESTIONNAIRE colorectal cancer surgery recovery Quality of life Internal medicine medicine Humans In patient Rectal resection Prospective Studies education RECTAL-CANCER colorectal resection Social functioning Aged Health related quality of life Aged 80 and over education.field_of_study business.industry General Medicine PROFILES Middle Aged medicine.disease Colorectal surgery humanities health-related quality of life PREHABILITATION Oncology Quality of Life Female TRIAL business Colorectal Neoplasms |
| Zdroj: | Journal of Surgical Oncology, 125(2), 217-226. Wiley-Liss Inc. |
| ISSN: | 0022-4790 |
| Popis: | Background and ObjectivesSurgery for colorectal cancer (CRC) negatively affects health-related quality of life (HRQoL). Addressing shortcomings in literature, the purpose of this study was to evaluate the impact of surgery for CRC on the course of HRQoL from baseline up to 2 years after diagnosis.MethodsIn this prospective, population-based study patients with newly diagnosed CRC were included between 2016 and 2019. HRQoL was assessed by the EORTC QLQ-C30 questionnaire over time both between and within subgroups of patients that underwent right-sided colonic, left-sided colonic, and rectal resection using linear mixed model analyses.ResultsThe study included 415 patients of whom 148 patients underwent right-sided colonic (36%), 147 left-sided colonic (35%), and 120 rectal resection (29%). Overall, HRQoL scores restored to baseline level 1 year after diagnosis. Impact of surgery seems to be more prominent in patients who underwent rectal resection, as they experienced more pain and had worse role and social functioning scores 4 weeks after surgery. Finally, among patients who underwent left-sided and rectal resection, physical functioning did not return to baseline level during follow-up.ConclusionThis study shows several differences (between-group and within-group) in HRQoL according to surgery type and offers perspective which patients may need additional support in the care pathway. |
| Databáze: | OpenAIRE |
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