Circadian rhythm of rectal motor complexes

Autor: W. R. Schouten, D. J. Bac, Johannes J.A. Auwerda
Rok vydání: 2001
Předmět:
Zdroj: Diseases of the Colon & Rectum. 44:1328-1332
ISSN: 0012-3706
DOI: 10.1007/bf02234793
Popis: PURPOSE: Prolonged rectal pressure recordings have revealed that the rectum exhibits typical bursts of regular pressure waves, also called rectal motor complexes. Although there is consensus regarding the characteristics of rectal motor complexes, their function is poorly understood. Furthermore, data regarding the circadian rhythm of these complexes are either lacking or conflicting. Therefore, we conducted a study to investigate the circadian rhythm of rectal motor complexes in fully ambulant subjects. Because a meal is a powerful and physiologic stimulus to elicit colonic pressure activity, we also studied the effect of a meal on these rectal motor complexes. METHODS: Prolonged ambulant anorectal pressure recordings were performed in 12 healthy volunteers (male:female ratio, 6:6; median age, 27 (range, 22–53) years). A total of 139 rectal motor complexes were observed in >300 hours of recording. RESULTS: All subjects exhibited rectal motor complexes during the daytime, whereas in five subjects, no rectal motor complexes were observed during sleep. The number of rectal motor complexes was significantly lower during sleep (diurnalvs. nocturnal, 8vs. 1 per subject,P
Databáze: OpenAIRE