Palladium-catalyzed decarboxylative ortho-amidation of O-methyl ketoximes with oxamic acids
| Autor: | Peng-Cheng Cui, Guan-Wu Wang, Kun Jing |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
010405 organic chemistry
Chemistry Metals and Alloys Intramolecular cyclization chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Medicinal chemistry Catalysis 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites Palladium |
| Zdroj: | Chemical Communications. 55:12551-12554 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/c9cc06460e |
| Popis: | The first palladium-catalyzed ortho-amidation of ketoximes has been developed with readily available, easy to handle and environment-friendly N,N-disubstituted oxamic acids as the amidation sources. When N-monosubstituted oxamic acids are used as the substrates, the formed ortho-amidated ketoximes undergo further intramolecular cyclization to provide 3-methyleneisoindolinones. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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