Expedited Partner Therapy in Female Adolescents: A Study of Acceptance and the Impact on Reinfection Rates
| Autor: | Kathryn E. Gannon-Loew, Emily Alexy, Cynthia Holland-Hall, Kenneth Jackson, Ashley M. Ebersole, Andrea E. Bonny |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Adolescent Sexually Transmitted Diseases Chlamydia trachomatis Dermatology medicine.disease_cause Gonorrhea Young Adult Chart review Internal medicine Medicine Humans Positive test Prospective Studies Young adult Retrospective Studies business.industry Public Health Environmental and Occupational Health Chlamydia Infections Infectious Diseases Sexual Partners Reinfection Cohort Trichomonas vaginalis Female Contact Tracing business |
| Zdroj: | Sexually transmitted diseases. 48(11) |
| ISSN: | 1537-4521 |
| Popis: | BACKGROUND Given the high risk of sexually transmitted infections (STIs) in adolescents and young adults (AYAs), this study evaluated expedited partner therapy (EPT) acceptance and STI reinfection rates in female AYA before and after availability of EPT. METHODS The pre-EPT cohort was a 3-year (November 2012 to November 2015) retrospective chart review of female AYA positive for Chlamydia trachomatis (CT) and/or Trichomonas vaginalis (TV) before introduction of EPT. An EPT protocol for CT and TV infections was implemented after legalization in Ohio in 2016. The post-EPT cohort was a prospective review of patients positive for CT and TV for 2 years (5/2016-5/2018) after EPT introduction. We evaluated EPT acceptance and compared reinfection rates (positive test 1-6 months after initial infection) in the pre-EPT versus post-EPT cohorts and by EPT acceptance. RESULTS Among patients offered EPT, 28% (67/237) with CT and 25% (24/97) with TV accepted EPT. There were no significant differences in the reinfection rates for CT or TV in the pre-EPT versus post-EPT cohorts (CT: 24% (57/240) vs 20% (38/192), P = 0.42; TV: 23% (22/97) versus 14% (12/87), P = 0.11). Although lower, reinfections rates were not significantly different among patients who accepted versus did not accept EPT (CT, 13% (6/48) vs 21% (23/110), P = 0.50 and TV, 6% (1/18) vs 18% (9/49), P = 0.69). CONCLUSIONS Despite the implementation of an EPT protocol, STI reinfection rates among female AYA remained high, and many declined EPT. Further research is needed to identify barriers to the provision and acceptance of EPT and ways to address these factors. |
| Databáze: | OpenAIRE |
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