Prevalence of Kawasaki Disease in Young Adults With Suspected Myocardial Ischemia

Autor: Peter E. Linz, Hannah H. Walford, Keshav R. Nayak, Jane C. Burns, John B. Gordon, Hoang-Anh L. Phan, Vera Trofimenko, Lori B. Daniels, Daryl B. Fick, Matthew S. Tjajadi, Susan Jimenez-Fernandez, Andrew M. Kahn
Rok vydání: 2012
Předmět:
Zdroj: Circulation. 125:2447-2453
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circulationaha.111.082107
Popis: Background— Up to 25% of patients with untreated Kawasaki disease (KD) and 5% of those treated with intravenous immunoglobulin will develop coronary artery aneurysms. Persistent aneurysms may remain silent until later in life when myocardial ischemia can occur. We sought to determine the prevalence of coronary artery aneurysms suggesting a history of KD among young adults undergoing coronary angiography for evaluation of possible myocardial ischemia. Methods and Results— We reviewed the medical histories and coronary angiograms of all adults Conclusions— Coronary sequelae of KD are present in 5% of young adults evaluated by angiography for myocardial ischemia. Cardiologists should be aware of this special subset of patients who may benefit from medical and invasive management strategies that differ from the strategies used to treat atherosclerotic coronary artery disease.
Databáze: OpenAIRE