Hepatitis C virus infection in haemodialysis patients
| Autor: | D. C. H. Harris, Anthony L. Cunningham, S. D. Roger, Evelyn Crewe |
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| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Resuscitation Blood transfusion Hepatitis C virus medicine.medical_treatment Hepacivirus Viral Nonstructural Proteins medicine.disease_cause Gastroenterology Serology Immunoenzyme Techniques Viral Proteins Renal Dialysis Internal medicine Internal Medicine medicine Prevalence Humans Blood Transfusion Hepatitis Antibodies Antigens Viral Infectivity biology business.industry virus diseases Hepatitis C Middle Aged medicine.disease Hepatitis B Core Antigens digestive system diseases Recombinant Proteins Cross-Sectional Studies Immunology biology.protein Kidney Failure Chronic Female Hemodialysis Antibody business |
| Zdroj: | Australian and New Zealand journal of medicine. 21(1) |
| ISSN: | 0004-8291 |
| Popis: | Antibody to hepatitis C has been variously detected in 1-20% of haemodialysis patients in recent studies from overseas. To determine the frequency of antibodies to the C100-3 protein of the hepatitis C virus (anti-HCV) a cross-sectional study was performed in 60 patients on maintenance haemodialysis in Western Sydney. Six patients (10%) were anti-HCV seropositive. Four of the six anti-HCV positive patients were also hepatitis B core antibody positive, compared with nine of 54 anti-HCV negative patients (p less than 0.05). All anti-HCV positive patients had received multiple blood transfusions. Serum alanine aminotransferase (ALT) was not useful as a screening test. Recent evidence suggests that anti-HCV seropositivity underestimates infectivity. |
| Databáze: | OpenAIRE |
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